Feedback is a key mechanism in biology and engineered systems, enabling robustness and adaptability. Single-cell controllers face scalability limits due to resource competition and interference. My research explores distributing feedback across multiple cell populations so that control tasks can be performed cooperatively — improving flexibility and robustness in synthetic microbial consortia.
See related publicationsNatural microbial communities divide labor and cooperate. Engineering such consortia requires mechanisms to maintain coexistence and desired relative abundances. I investigate design strategies for ratiometric control — methods that regulate the composition of a community so that multiple strains persist and perform their roles reliably over time.
See related publicationsLarge ensembles of interacting agents exhibit emergent collective behavior. Building descriptive models and designing validated control strategies requires balancing fidelity and tractability. My work focuses on parametrizing models for complex networks and developing distributed control and coordination methods to steer collective dynamics toward desired behaviours.
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